教員・教室員について
社会環境医学講座 連携腫瘍学分野 助教
名前 | 大村 洋文(おおむら ひろふみ) |
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卒業年 | 2013(平成25)年 |
学位取得年月 | 2021年3月 |
専門領域 | 腫瘍内科 |
資格 | 日本内科学会認定内科医・総合内科専門医・指導医 日本臨床腫瘍学会がん薬物療法専門医 日本がん治療認定医機構がん治療認定医 |
所属学会 | 日本内科学会、日本臨床腫瘍学会、日本癌学会、日本癌治療学会、 日本消化器病学会、日本乳癌学会、日本緩和医療学会 |
略歴
2013年~2015年 |
国立病院機構九州医療センター 臨床研修医 |
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2015年~2017年 |
国立病院機構九州医療センター 腫瘍内科レジデント |
2017年~2021年 |
九州大学大学院医学系学府 医学専攻 博士課程 |
2021年~2022年 |
九州大学病院 血液・腫瘍・心血管内科 医員 |
2022年~2023年 |
九州大学病院別府病院 内科 医員 |
2023年~ |
九州大学大学院医学研究院 社会環境医学講座 連携社会医学分野 助教 |
代表的業績
- Takeda M, Ohno S, Tahara M, Takeuchi H, Shirogane Y, Ohmura H, Nakamura T, Yanagi Y. Measles
viruses possessing the polymerase protein genes of the Edmonston vaccine strain exhibit attenuated gene
expression and growth in cultured cells and SLAM knock-in mice. J Virol. 2008;82(23):11979-11984. - Ohmura H, Uchino K, Kajitani T, Sakamoto N, Baba E. Predictive value of the modified Glasgow Prognostic
Score for the therapeutic effects of molecular-targeted drugs on advanced renal cell carcinoma. Mol Clin
Oncol. 2017;6(5):669-675. - Inadomi K, Kusaba H, Matsushita Y, Matsushita Y, Tanaka R, Mitsugi K, Arimizu K, Hirano G, Makiyama A,
Ohmura H, Uchino K, Hanamura F, Shibata Y, Kuwayama M, Esaki T, Takayoshi K, Arita S, Ariyama H,
Akashi K, Baba E. Efficacy and Safety Analysis of Oxaliplatin-based Chemotherapy for Advanced Gastric
Cancer. Anticancer Res. 2017;37(5):2663-2671. - Yamaguchi K, Mishima K, Ohmura H, et al. Activation of central/effector memory T cells and T-helper 1
polarization in malignant melanoma patients treated with anti-programmed death-1 antibody. Cancer Sci.
2018;109(10):3032-3042. - Nakano M, Ito M, Tanaka R, Yamaguchi K, Ariyama H, Mitsugi K, Yoshihiro T, Ohmura H, Tsuruta N,
Hanamura F, Sagara K, Okumura Y, Nio K, Tsuchihashi K, Arita S, Kusaba H, Baba. PD-1+ TIM-3+ T cells in
malignant ascites predict prognosis of gastrointestinal cancer. Cancer Sci. 2018;109(9):2986-2992. - Makiyama A, Arimizu K, Hirano G, Makiyama C, Matsushita Y, Shirakawa T, Ohmura H, Komoda M, Uchino
K, Inadomi K, Arita S, Ariyama H, Kusaba H, Shinohara Y, Kuwayama M, Kajitani T, Hisanobu O, Esaki T,
Akashi K, Baba E. Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer. Gastric
Cancer. 2018;21(3):464-472. - Tsuruta N, Tsuchihashi K, Ohmura H, et al. RNA N6-methyladenosine demethylase FTO regulates PD-L1
expression in colon cancer cells. Biochem Biophys Res Commun. 2020;530(1):235-239. - Yamaguchi K, Ito M, Ohmura H, et al. Helper T cell-dominant tertiary lymphoid structures are associated
with disease relapse of advanced colorectal cancer. Oncoimmunology. 2020;9(1):1724763. - Ohmura H, Yamaguchi K, Hanamura F, et al. OX40 and LAG3 are associated with better prognosis in
advanced gastric cancer patients treated with anti-programmed death-1 antibody. Br J Cancer.
2020;122(10):1507-1517. - Ohmura H, Ito M, Uchino K, et al. Methylation of drug resistance-related genes in
chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer. FEBS Open Bio.
2020;10(1):147-157. - Tanoue K, Tamura S, Kusaba H, Shinohara Y, Ito M, Tsuchihashi K, Shirakawa T, Otsuka T,
Ohmura H, Isobe T, Ariyama H, Koreishi S, Matsushita Y, Shimokawa H, Tanaka R, Mitsugi K, Akashi K,
Baba E. Predictive impact of C-reactive protein to albumin ratio for recurrent or metastatic head and
neck squamous cell carcinoma receiving nivolumab. Sci Rep. 2021;11(1):2741. - Kusaba H, Moriyama S, Hieda M, Ito M, Ohmura H, Isobe T, Tsuchihasi K, Fukata M, Ariyama H, Baba E.
IMPROVE bleeding score predicts major bleeding in advanced gastrointestinal cancer patients with venous
thromboembolism. Jpn J Clin Oncol. 2022;52(10):1183-1190. - Taguchi R, Tsuchihashi K, Okumura Y, Nakano M, Yoshihiro T, Ohmura H, Tsuruta N,
Hanamura F, Yamaguchi K, Ito M, Ariyama H, Kusaba H, Akashi K, Baba E.
Thrombocytopenia Caused by Dexamethasone in a Patient with Colorectal Cancer.
Intern Med. 2020;59(20):2571-2575. - Ueno S, Uenomachi M, Kusaba H, Ito M, Suzuki K, Ohmura H, Tsuchihasi K, Ariyama H,
Akashi K, Baba E. Improvement in recurring nivolumab-induced pneumonitis with repetitive
administration of infliximab in a patient with head and neck cancer: A case report. Mol Clin
Oncol. 2021;15(4):221. - Yamaguchi K, Tsuchihashi K, Tsuji K, Kito Y, Tanoue K, Ohmura H, Ito M, Isobe T,
Ariyama H, Kusaba H, Akashi K, Baba E. Prominent PD-L1-positive M2 macrophage
infiltration in gastric cancer with hyper-progression after anti-PD-1 therapy: A case report.
Medicine (Baltimore). 2021;100(19):e25773. - Ohmura H, Masuda T, Mimori K, Baba E, Horiuchi T. A case of malignant phyllodes tumor that responded to pazopanib and developed pneumothorax. Int Cancer Conf J. 2022;12(1):31-35.
- Tsuchihashi K, Kusaba H, Yoshihiro T, Fujiwara T, Setsu N, Endo M, Matsumoto Y, Imajima T, Shinohara Y, Ito M, Yamaga S, Tanoue K, Arimizu K, Ohmura H, Hanamura F, Yamaguchi K, Isobe T, Ariyama H, Nakashima Y, Akashi K, Baba E. Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin. Sci Rep. 2020;10(1):20896.
- Masuda T, Ueo H, Okumura Y, Kai Y, Ando Y, Masuguchi K, Kitagawa M, Kitagawa A, Hayashi N, Tsuruda Y, Hisamatsu Y, Suehiro S, Ohmura H, Fujiyoshi K, Tanaka F, Mimori K. Dynamic Changes in Peripheral Systemic Immunity Markers During Chemotherapy in HER2-negative Advanced Breast Cancer. Cancer Genomics Proteomics. 2023 Mar-Apr;20(2):182-194.
- Ohmura H, Tobo T, Mimori K, Baba E, Horiuchi T. Trousseau's Syndrome with Advanced Neuroendocrine Carcinoma of Colon: A Case Report. Case Rep Oncol. 2023 Jul 3;16(1):484-490.
- Uehara K, Tanoue K, Yamaguchi K, Ohmura H, Ito M, Matsushita Y, Tsuchihashi K, Tamura S, Shimokawa H, Isobe T, Shibata Y, Ariyama H, Tanaka R, Kusaba H, Yamamoto H, Oda Y, Akashi K, Baba E. Preferential B cell differentiation by combined immune checkpoint blockade for renal cell carcinoma is associated with clinical response and autoimmune reactions. Cancer Immunol Immunother. 2023 Nov;72(11):3543-3558.
- Ohmura H, Kondo M, Uenomachi M, Ariyama H, Ito M, Tsuchihashi K, Ayano M, Niiro H, Akashi K, Baba E. Case Report: Resolution of remitting seronegative symmetrical synovitis with pitting edema during nivolumab therapy for gastric cancer. Front Oncol. 2023 Oct 5;13:1260818.