代表的業績

1.  Wakeham D, Ivey E, Saland S, Lewis J, Palmer D, Morris M, Bleich J, Weyand P, Brazile P, Hearon CJr., Sarma S, MacNamara J, Hieda M, and Levine DB The effects of synchronizing foot strike and cardiac phase on exercise hemodynamics in patients with cardiac resynchronization therapy: a within-subjects pilot-study to fine-tune cardio-locomotor coupling for heart failure Circulation 2023;148:2008-2016. PMID: 37830218
2. MacNamara J, Dias K, Hearon C Jr., Ivey E, Delgado V, Saland S, Samels M, Hieda M, Turer A, Link M, Sarma S, Levine DB Randomized Controlled Trial of Moderate and High Intensity Exercise Training in Patients with Hypertrophic Cardiomyopathy: Effects on Fitness and Cardiovascular Response to Exercise Journal of American Heart Association 2023;12:e031399. PMID: 37830338
3. Futami S, Hieda M, Fukata M, Shiose A. A rare case of cardiac myxoma with light bulb-like cystic morphology: a case report. European Heart Journal -Case Reports  2023;7:ytad331. PMID: 37547377
4. Sarma S, MacNamara JP, Hieda M, Howden EJ, Lawley JS, Livingston S, Samels M and Levine BD. SERCA2a Agonist Effects on Cardiac Performance During Exercise in Heart Failure With Preserved Ejection Fraction. JACC: Heart Failure;2023;11:760-771. doi: doi:10.1016/j.jchf.2023.02.006, PMID: 37086245
5. Sato T, Hieda M, Futami S, Fukata M, Shiose A. Evaluation of coronary flow is useful in patients with left coronary cusp thrombus formation after left ventricular assist device implantation. European Heart Journal - Case Reports 2023;7:ytad025. doi: 10.1093/ehjcr/ytad025. PMID: 36727124
   doi: 10.1093/ehjcr/ytad025 PMID: 36727124 * Corresponding author
6. McKenna ZJ, Moralez G, Romero SA, Hieda M, Huang M, Cramer MN, Sarma S, MacNamara JP, Jaffery MF, Atkins WC, Foster J, Crandall CG.　Cardiac Remodeling in Well-Healed Burn Survivors after Six Months of Unsupervised Progressive Exercise Training Journal of Applied Physiology 2023 Jan 12. doi: 10.1152/japplphysiol.00630.2022. PMID: 36633867
7. Maruyama T, Hieda M, Eiraku K, Uozumi Y, Nomura H Constipation and heart failure: An overlooked but important linkage. Geriatrics & Gerontology International 2023 Jan 25. doi: 10.1111/ggi.14545. PMID: 36697380
8. Moriyama S, Hieda M, Kisanuki M, Kawano S, Yokoyama T, Fukata M, Kusaba H, Maruyama T, Baba E, and Akashi K, Fukuda H. Both New-onset and Pre-existing Hypertension indicate favorable Clinical Outcomes in Patients treated with anti-VEGF Therapy. Circulation Journal 2022 Dec 6. doi: 10.1253/circj.CJ-22-0628. PMID: 36476830　 PMID: 36476830　* Corresponding author　
9. Moriyama S, Hieda M, Kisanuki M, Kawano S, Yokoyama T, Fukata M, Kusaba H, Maruyama T, Baba E, and Akashi K, Fukuda H. Effect of renin-angiotensin system inhibitors in patients with cancer treated with anti-VEGF therapy. Open heart 2022 Dec;9(2):e002135.　PMID: 36600585　* Corresponding author
10. Hieda M, Maruyama T. Importance of pulsatility in left ventricular assist device　 Series on Biomechanics 2022;36:28-37. * Corresponding author
11. Fukudome Y, Hieda M, Masui S, Yokoyama T, Futami S, Moriyama S, Irie K, Fukata M, Ushijima T, Shiose A, Akashi K. Case Report: Bronchogenic Cyst in the Right Atrium of a Young Woman. Front Cardiovasc Med. 2022 May 27;9:915876.　 PMID: 35711360 * Corresponding author
12. Fischer M, Moralez G, Sarma S, MacNamara J, Cramer M, Huang M, Romero S, Hieda M, Shibasaki M, Ogoh S, and Crandall C. Altered CARDIAC β1 responsiveness in hyperthermic OLDER ADULTS. Am J Physiol Regul Integr Comp Physiol. 2022 Oct 1;323(4):R581-R588. PMID: 36094450
13. Eiraku K, Uozumi Y, Hieda M, Maruyama T, Nomura H. A Senile Case of Heart Failure Associated with Hypermagnesemia Induced by Magnesium-Containing Laxative Agent　 Geriatr Gerontol Int. 2022 Oct;22(10):897-899. PMID: 36071490
14. MacNamara J, Dias K, Hearon C, Hieda M, Turer A, Link M, Sarma S, and Levine B.　 Limits to Submaximal and Maximal Exercise in Patients with Hypertrophic Cardiomyopathy Journal of Applied Physiology 2022 Oct 1;133(4):787-797.　PMID: 35952351
15. Hieda M, Maruyama T. Acquired von Willebrand syndrome and hemocompatibility-　related adverse events in patients with left ventricular assist device. Journal of Biorheology 2022;36:12-22. * Corresponding author
16. Kusaba H, Moriyama S, Hieda M, Ito M, Ohmura H, Isobe T, Tsuchihashi K, Fukata M, Ariyama H, Baba E. IMPROVE bleeding score predicts major bleeding in advanced gastrointestinal cancer patients with venous thromboembolism. Jpn J Clin Oncol, 2022, 2022 Jun 29;hyac103. doi: 10.1093/jjco/hyac103.　 PMID: 35766165
17. Moriyama S, Fukata M, Hieda M, Yokoyama T, Yoshimoto G, Kusaba H, Nakashima Y, Miyamoto T, Maruyama T, Akashi K. Early-onset cardiac dysfunction following allogeneic haematopoietic stem cell transplantation. Open Heart 2022 May;9(1):e002007. doi: 10.1136/openhrt-2022-002007. PMID: 35606045
18. Hieda M, Levine BD. Response by Hieda and Levine to Letter Regarding Article, "One-Year Committed Exercise Training Reverses Abnormal Left Ventricular Myocardial Stiffness in Patients With Stage B Heart Failure With Preserved Ejection Fraction" Circulation 2022 Mar;145(9):e644. PMID: 35226555
19. Maruyama T, Hieda M, Mawatari S, and Fujino T. Rheological Abnormalities in Human Erythrocytes Subjected to Oxidative Inflammation. Frontiers in Physiology 2022 Feb 23;13:837926. doi: 10.3389/fphys.2022.837926, PMID: 35283782
20. Hatakeyama K, Hieda M, Semba Y, Moriyama S, Wang Y, Maeda T, Kato K, Miyamoto T, Akashi K, Kikushige Y. TET2 Clonal Hematopoiesis is Associated with Anthracycline-Induced Cardiotoxicity in Patients with Lymphoma. JACC CardioOncology 2022;4:141-143. PMID: 35492814
21. Hearon CM Jr, Dias KA, MacNamara JP, Hieda M, Mantha Y, Harada R, Samels M, Morris M, Szczepaniak LS, Levine BD, Sarma S. 1 Year HIIT and Omega-3 Fatty Acids to Improve Cardiometabolic Risk in Stage-A Heart Failure. JACC HF 2022 Apr;10(4):238-249. PMID: 35361442
22. Maruyama T, Hieda M, Koyama T, Kawa T, and Fujino T. Estimation of Red Cell Filterability Using Two-Step Nickel Mesh Filtration System: A Feasibility Study of Tandem Filtration. Nihon Reoroji Gakkaishi 2022;50:119-125. DOI https://doi.org/10.1678/rheology.50.119
23. Mantha Y, Futami S, Moriyama S, and Hieda M. Valvulo-Arterial Impedance and Dimensionless Index for Risk Stratifying Patients with Severe Aortic Stenosis. Frontier in Cardiovascular Medicine 2021;8:742297. PMID: 34926605 * Corresponding author
24. Hieda M, Sarma S, Hearon CM Jr, MacNamara JP, Dias KA, Samels M, Palmer D, Livingston S, Morris M, Levine BD. One-Year Committed Exercise Training Reverses Abnormal Left Ventricular Myocardial Stiffness in Patients with Stage-B HFpEF. Circulation 2021 144(12):934-946. PMID: 34543068
25. Maruyama T, Hieda M. Erythrocyte damage observed in patients with heart valve replacement: Investigation by morphological, biochemical and hemorheological techniques. J Biorheol 2021;35(2):57–61. DOI 10.17106/jbr.35.57
26. Tomio Tran, Akshay Muralidhar, Kendall Hunter, Cullen Buchanan, Greg Coe, Hieda M, Christine Tompkins, Matthew Zipse, Melanie J Spotts, Stephanie G Laing, Kristina Fosmark, Jordan Hoffman, Amrut V Ambardekar, Eugene E Wolfel, Justin Lawley, Benjamin Levine, Wendy M Kohrt, Jay Pal William K Cornwell 3^rd. Right ventricular function and cardiopulmonary performance among patients with heart failure supported by durable mechanical circulatory support devices. J Heart Lung Transplant. 2021 Nov 22;S1053-2498(20)31841-6. PMID: 33281029
27. Hardin EA, Stoller D, Lawley J, Howden EJ, Hieda M, Pawelczyk J, Jarvis S, Prisk K, Sarma S, Levine BD. Noninvasive Assessment of Cardiac Output: Accuracy and Precision of the Closed-Circuit Acetylene Rebreathing Technique for Cardiac Output Measurement. J Am Heart Assoc. 2020 Sep;9(17):e015794. PMID: 32851906
28. Cramer MN, Hieda M, Huang M, Moralez G, Crandall CG. Dietary nitrate supplementation does not influence thermoregulatory or cardiovascular strain in older individuals during severe ambient heat stress. Exp Physiol. 2020 Aug 20. doi: 10.1113/EP088834. PMID: 32816341
29. Mantha Y, Harada R, Hieda M, Assaf A, Tatiraju U, Feldman M and Kawalsky D. Masson Tumor in the Left Atrial Appendage Presenting as Cardioembolic Cerebral Infarction. JACC: Case Reports 2020 DOI: 10.1016/j.jaccas.2020.05.044. PMID: 34317091
30. Hieda M, Esposito G, Bossone E. Novel Clinical and Pathophysiologic Concepts in Cardiovascular Emergencies. Heart Fail Clin. 2020 Jul;16(3):xi-xii. doi: 10.1016/j.hfc.2020.04.001. PMID: 32503759
31. Rao P, Katz D, Hieda M, Sabe M. How to Manage Temporary Mechanical Circulatory Support Devices in the Critical Care Setting: Translating Physiology to the Bedside. Heart Fail Clin. 2020 Jul;16(3):283-293. doi: 10.1016/j.hfc.2020.03.001. PMID: 32503752
32. Hieda M, Goto Y. Cardiac Mechanoenergetics in Patients with Acute Myocardial Infarction: From Pressure-Volume Loop Diagram Related to Cardiac Oxygen Consumption. Heart Fail Clin. 2020 Jul;16(3):255-269. doi: 10.1016/j.hfc.2020.02.002. PMID: 32503750
33. Hieda M. Non-Invasive Positive Pressure Ventilation for Acute Decompensated Heart Failure. Heart Fail Clin. 2020 Jul;16(3):271-282. doi: 10.1016/j.hfc.2020.02.005. PMID: 32503751 * Corresponding author
34. Maruyama T, Arita T, Yokoyama T, Hieda M, Fukata M, Fujino T, Mawatari S, Akashi K. Impaired deformability and association with density distribution of erythrocytes in patients with type 2 diabetes mellitus under treatment. Clin Hemorheol Microcirc. 2020 May 12. doi: 10.3233/CH-200873. Online ahead of print. PMID: 32417767
35. Hieda M, Esposito G, Bossone E. The Latest Clinical Understandings and Theory of the Cardiovascular Systems for Cardiovascular Emergencies and Their Management. Heart Fail Clin. 2020 Apr;16(2):ix-x. doi: 10.1016/j.hfc.2020.01.001. PMID: 32143769
36. Mantha Y, Harada R, Hieda M. Management of Common Cardiovascular Emergencies in Critically Ill Patients. Heart Failure clinics 2020;16:153-166. PMID: 32143760 * Corresponding author
37. Harada R, Mantha Y, Hieda M. Back to Basics: Key Physical Examinations and Theories in Patients with Heart Failure. Heart Failure clinics 2020; 16:139-151.  PMID: 32143759 * Corresponding author
38. Mantha Y, Feldman M, Assaf A, Harada R, Musselman D, Hieda M, Kawalsky D. Anomalous Origin of Right Coronary Artery from Pulmonary Artery (ARCAPA) in a Middle- Aged Woman. JACC case report 2020 DOI: 10.1016/j.jaccas.2020.01.008. PMID: 34317265
39. Mada PK, Malus EM, Parvathaneni A, Chen B, Castano B, Adley B, Moore M, Hieda M, Alam M, Feldman M, and King J. Impact of Treatment with Direct Acting Antiviral Drugs on Glycemic Control in Patients with Hepatitis C and Diabetes Mellitus. Clin Hemorheol Microcirc. 2020 May 12. doi: 10.3233/CH-200873. PMID: 32417767
40. Moghadam N, Hieda M, Ramey L, Levine BD, Guilliod R. Hyperbaric Oxygen Therapy in Sports Musculoskeletal Injuries. Med Sci Sports Exerc. 2020 Jun;52(6):1420-1426. doi: 10.1249/MSS.0000000000002257. PMID: 31876671
41. Hieda M, Satyam S, Hearon Jr. C, Dias K, Martinez J, Samels M, Everding B, Palmer D, Livingston S, Morris M, Howden E, Levine BD. Increased Myocardial Stiffness in Patients With High-Risk Left Ventricular Hypertrophy: The Hallmark of Stage-B Heart Failure With Preserved Ejection Fraction. Circulation 2020 Jan 14;141(2):115-123. PMID: 31865771
42. Hearon Jr. C, Ph.D; Sarma S, Dias K, Hieda M, Levine DB. Impaired oxygen uptake kinetics in heart failure with preserved ejection fraction. Heart 2019 pii: heartjnl-2019-314797. doi: 10.1136/heartjnl-2019-314797. PMID: 31208971
43. Aiad N, Hearon C, Hieda M, Dias K; Levine DB, and Sarma S. Mechanisms of Left Atrial Enlargement in Obesity - The Influence of Left Ventricular Remodeling. American Journal of Cardiology 2019;124:442-447. PMID: 31133275
44. Hieda M, Yoo JK, Badrov BM, Parker SR, Anderson HE, Wiblin LJ, Kawalsky J, North SC, Suris A, and Fu Q. Reduced Left Ventricular Diastolic Function in Women with Post-Traumatic Stress Disorder. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2019;317:108-112. PMID: 30995071
45. Samuel TJ, Nelson MD, Nasirian A, Jaffery M, Moralez G, Romero SA, Cramer MN, Huang M, Kouda K, Hieda M, Sarma S and Crandall CG. Cardiac Structure and Function in Well-Healed Burn Survivors. Journal of Burn Care & Research 2019;40:235-241. PMID: 30649454
46. Badrov BM, Park S, Yoo JK, Hieda M, Okada Y, Jarvis SS, Stickford AS, Best SA, Nelson DB, and Fu Q, MD. Role of Corin in blood pressure regulation in normotensive and hypertensive pregnancy: a prospective study. Hypertension 2019;73:432-439. PMID: 30580684
47. McNamara DA, Aiad N, Howden E, Hieda M, Link MS, Everding B, Palmer D, Samels M, Ng J, Adams-Huet B, Mildred O, Sarma S, and Levine BD. Left Atrial Electromechanical Remodeling Following 2 Years of High-Intensity Exercise Training in Sedentary Middle-Aged Adults. Circulation 2018;139:1507-1516. PMID: 30586729
48. Hieda M, Howden E, Sarma S, Cornwell W, Lawley J, Tarumi T, Palmer D, Samels M, Everding B, Livingston S, Fu Q, Zhang R, and Levine BD. The Impact of 2-Years of High Intensity Exercise Training on a Model of Integrated Cardiovascular Regulation. Journal of Physiology 2019;597:419-429. PMID: 30387144
49. Hieda M, Howden E, Shibata S, Fujimoto N, Bhella PS, Hastings JL, Tarumi T, Satyam S, Fu Q, Zhang R, Levine BD. Impact of Lifelong Exercise Training Dose on Ventricular-Arterial Coupling. Circulation 2018;138:2638-2647. PMID: 30571254
49. Circulation 2018;138:2638-2647. PMID: 30571254
50. Hieda M, Yoo JK, Sun D, Okada Y, Parker R, Roberts-Reeves M, Adams-Huet B, Nelson D, Levine DB, and Fu Q. Time Course of Changes in Maternal Left Ventricular Function during Subsequent Pregnancy in Women with a History of Gestational Hypertensive Disorders. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2018;315:587-594. PMID: 29897820
51. Opondo M, Aiad N, Cain M, Sarma S, Howden E, Stoller D, Ng J, Rijckevorsel B, Hieda M, Tarumi T, Palmer D, Benjamin D. Levine. Does High Intensity Endurance Training Increase the Risk of Atrial Fibrillation? A Longitudinal Study of Left Atrial Structure and Function. Circulation: Arrhythmia and Electrophysiology 2018;11:e005598. doi: 10.1161/CIRCEP.117.005598. PMID: 29748195
52. Hieda M, Parker J, Rajabi T, Fujimoto N, Bhella PS, Prasad A, Hastings JL, Sarma S, Levine BD. Left Ventricular Volume-Time Relation in Patients With Heart Failure With Preserved Ejection Fraction. Am J Cardiol 2018;121(5):609-614.  doi: 10.1016/j.amjcard.2017.11.033. PMID: 29306483
53. Hieda M; Howden E; Shibata S; Tarumi T; Lawley J; Hearon C Jr.; Palmer D; Fu Q; Zhang R; Sarma S; Benjamin D. Levine. Pre-load Corrected Dynamic Starling Mechanism in Patients with Heart Failure with Preserved Ejection Fraction. Journal of Applied Physiology 2018 Jan 1;124(1):76-82. doi: 10.1152/japplphysiol.00718.2017. PMID: 29051333
54. Howden E, Carrick-Ranson G, Sarma S, Hieda M, Fujimoto N, Benjamin D. Levine. Effect of Sedentary Aging and Lifelong Exercise on Left Ventricular Systolic Function. Medicine & Science in Sports & Exercise 2018 Mar;50(3):494-501. doi: 10.1249/MSS.0000000000001464. PMID: 29077636
55. Yoo JK, Okada Y, Best SA, Parker RS, Hieda M, Levine BD, Fu Q. Left ventricular remodeling and arterial afterload in older women with uncontrolled and controlled hypertension. Menopause 2018 May;25(5):554-562. PMID: 29257033
56. Ogoh S, Moralez G, Washio T, Sarma S, Hieda M, Romero S, Cramer M, Shibasaki M, and Crandall C. Effect of increases in cardiac contractility on cerebral blood flow in humans. American Journal of Physiology Heart and Circulatory Physiology 2017;313:H1155-H1161. PMID: 28916637
57. Hieda M, Seguchi O, Mutara Y, Sunami H, Sato T, Yanase M, Hiroki H, Fujita T, Nakatani T. Acute response test to adaptive servo-ventilation, a possible modality to assessing the reversibility of pulmonary vascular resistance. J Artif Organs. 2015;18:280-283. PMID: 25809453
58. Hieda M, Sata M, Nakatani T. The Importance of the Management of Infectious Complications for Patients with Left Ventricular Assist Device. Healthcare. 2015;3:750-756. PMID: 27417794
59. Sato T, Seguchi O, Iwashima Y, Yanase M, Nakajima S, Hieda M, Watanabe T, Sunami H, Murata Y, Hata H, Fujita T, Kobayashi J, Nakatani T. Serum Brain Natriuretic Peptide Concentration 60 Days after Surgery as a Predictor of Long-term Prognosis in Patients Implanted with a Left Ventricular Assist Device. ASAIO J. 2015;61:373-378. PMID: 26120957
60. Watanabe T, Seguchi O, Nishimura K, Fujita T, Murata Y, Yanase M, Sato T, Sunami H, Nakajima S, Hisamatsu E, Sato T, Kuroda K, Hieda M, Wada K, Hata H, Ishibashi-Ueda H, Miyamoto Y, Fukushima N, Kobayashi J, Nakatani T. Suppressive effects of conversion from mycophenolate mofetil to everolimus for the development of cardiac allograft vasculopathy in maintenance of heart transplant recipients. Int J Cardiol. 2015;203:307-314. PMID: 26523360
61. Hieda M, Sata M, Seguchi O, Yanase M, Murata Y, Sato T, Sunami H, Nakajima S, Watanabe T, Hori Y, Wada K, Hata H, Fujita T, Kobayashi J, Nakatani T. Importance of Early Appropriate Intervention including Antibiotics and Wound care for Device-related Infection in Patients with Left Ventricular Assist Device. Transplant Proc. 2014;46:907-910. PMID: 24767378
62. Nakajima S, Seguchi O, Murata Y, Fujita T, Hata H, Yamane T, Hieda ;, Watanabe T, Sato T, Sunami H, Yanase M, Kobayashi J, Nakatani T. Left coronary artery occlusion caused by a large thrombus on the left coronary cusp in a patient with a continuous-flow ventricular assist device. J Artif Organs. 2014;17:197-201. PMID: 24509915
63. Suwa H, Seguchi O, Fujita T, Murata Y, Hieda M, Watanabe T, Sato T, Sunami H, Yanase M, Hata H, Nakatani T. Paracorporeal ventricular assist device as a bridge to transplant candidacy in the era of implantable continuous-flow ventricular assist device. J Artif Organs. 2014 Mar;17(1):16-22. PMID: 24096597
64. Sato T, Seguchi O, Morikawa N, Hieda M, Watanabe T, Sunami H, Murata Y, Yanase M, Hata H, Fujita T, Nakatani T. A heart transplant candidate with severe pulmonary hypertension and extremely high pulmonary vascular resistance. J Artif Organs. 2013 Jun;16(2):253-7. PMID: 23443326
65. Kongphanich A, Hieda M, Kurokawa K, Murata T, Kobayashi N.　Overcoming the blockade at the upstream of caspase cascade in Fas-resistant HTLV-I-infected T cells by cycloheximide.　Biochem Biophys Res Commun. 2002;294(3):714-8. PMID: 12056829